078 Sensory nerve abnormalities in motor neuron disease
نویسندگان
چکیده
منابع مشابه
Conduction velocity and refractory period of single motor nerve fibres in motor neuron disease.
Electromyographic single motor unit recordings were used to study the axonal conduction velocity and the axonal refractory period of 60 motor units in patients with severe motor neuron disease. Eighteen per cent of the motor units had abnormally low axonal conduction velocity probably due to secondary degenerative changes. Thirty-two per cent of the motor units had abnormally long axonal refrac...
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Twenty-seven of 42 patients with motor neuron disease had significant pain. The nature and duration of the pain are described along with an illustrative case-report. The aetiology and most effective treatment of this common complication of motor neuron disease remain unclear.
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Increasing evidence suggests that the pathogenesis of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) is not restricted to the neurons but attributed to the abnormal interactions of neurons and surrounding glial and lymphoid cells. These findings led to the concept of non-cell autonomous neurodegeneration. Neuroinflammation, which is mediated by activated glial cells an...
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Hadjikoutis and Wiles draw attention to a number of circumstances in which the serum chloride and bicarbonate can be misleading. They do not mention that they will also be misleading if they are measured when hypercapnia is increasing or decreasing. An exacerbation of hypercapnia will take 4 – 6 days to raise the serum bicarbonate and lower the serum chloride to new steady levels. 1 How long it...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2019
ISSN: 0022-3050,1468-330X
DOI: 10.1136/jnnp-2019-anzan.66